Research Guides
Structured, evidence-based guides for researchers working with peptide reference standards in vitro.
Serve as the primary long-form reference material on the site — one guide, one topic, one clear reading pathway.
- What is Retatrutide?
Introductory reference on Retatrutide (LY3437943) — a triple-agonist investigational peptide referenced in incretin pharmacology literature.
- Retatrutide Mechanism of Action
Receptor-level explanation of Retatrutide's activity at GLP-1R, GIPR and GCGR as reported in the published preclinical and clinical literature.
- GLP-1 Receptor Explained
Overview of the GLP-1 receptor: a Class B G-protein-coupled receptor central to incretin pharmacology and to a growing family of research peptides.
- GIP Receptor Explained
Overview of the GIP receptor: a class B G-protein-coupled receptor engaged by dual and triple incretin-agonist research peptides.
- Glucagon Receptor Explained
Overview of the glucagon receptor (GCGR): classification, hepatic signalling and its role as the third receptor in triple-agonist research peptides.
- Triple Agonists Explained
Educational overview of triple GLP-1 / GIP / glucagon receptor agonists — pharmacological rationale, structural strategy and comparison to single- and dual-agonist analogues.
How to read the Research Hub
- STEP 1Start HereOrient yourself in the Research Hub
- STEP 2MechanismUnderstand the receptor pathway
- STEP 3CompoundRead the compound monograph
- STEP 4Laboratory MethodConfirm handling and analytical procedure
- STEP 5ComparisonContrast with related compounds
- STEP 6Related ReadingContinue with linked guides and literature