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GLOSSARY

Certificate of Analysis

Also known as: CoA; COA

Batch-specific quality document that reports identity, purity, endotoxin content and related analytical results for a manufactured peptide lot.

DEFINITION

A Certificate of Analysis (CoA) is a batch- specific quality document issued by the manufacturer of a research peptide summarising the analytical results generated during release testing. It provides the primary evidence that the supplied material meets its declared specifications.

A CoA typically reports: identity (LC-MS observed vs theoretical mass), purity (HPLC %), sequence confirmation, counterion / salt content, water content (Karl Fischer), endotoxin content (LAL, EU / mg where relevant), appearance, batch and lot number, manufacture and expiry dates, and recommended storage conditions.

WHY IT MATTERS

The CoA is the single artefact tying a specific lot to a specific set of analytical measurements — indispensable to laboratory record-keeping and reproducibility.

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Published: 2026-08-12Updated: 2026-08-12